| Date | Transaction |
| 02-28-2062 | Frank Mackie has retired from football. |
| 09-05-2061 | The Pittsburgh Polecats have waived Frank Mackie. |
| 09-05-2061 | The Pittsburgh Polecats have moved Buster Chops, Rich Ware, Harvey Potteiger, Jon Howard, Buckets Baccaglio, Brad Lundell, and Akin Hill to the active roster. The Pittsburgh Polecats have moved Tom Klein, Gene Thomas, Dick Okeafor, Connie Stogie-Wagon, and Frank Mackie to the inactive roster. |
| 09-13-2060 | The Pittsburgh Polecats have moved Frank Mackie, Dick Okeafor, and Ben Wade to the active roster. The Pittsburgh Polecats have moved Larry Osborne, Joe Cherry, and Bill Abbruzzi to the inactive roster. |
| 09-13-2060 | The Pittsburgh Polecats have acquired Frank Mackie from the waiver wire. |
| 09-12-2060 | The St. Louis Cardinals have automatically waived Frank Mackie to comply with the 53-man roster limit. |
| 08-09-2060 | The St. Louis Cardinals have moved Torry Weary, Curtis Sanders, and Chuck Daniels to the active roster. The St. Louis Cardinals have moved Henri Creswell, Frank Mackie, and Antonio Rieves to the inactive roster. |
| 10-06-2059 | The St. Louis Cardinals have moved Frank Mackie and Ron Reid to the active roster. The St. Louis Cardinals have moved Barrett Lorenti and Edd Goodman to the inactive roster. |
| 08-31-2059 | The St. Louis Cardinals have moved Tom Johnson to the active roster. The St. Louis Cardinals have moved Frank Mackie to the inactive roster. |
| 08-31-2059 | Frank Mackie of the St. Louis Cardinals is injured with an ankle ligament sprain and is expected to be out for approximately 30 days. |
| 09-02-2058 | The St. Louis Cardinals have moved Frank Mackie, Ron Reid, and Rico Cabrinha to the active roster. The St. Louis Cardinals have moved Edd Goodman, Anthony Fischer, and Tom Johnson to the inactive roster. |
| 08-05-2058 | The St. Louis Cardinals have moved Tom Johnson to the active roster. The St. Louis Cardinals have moved Frank Mackie to the inactive roster. |
| 10-29-2057 | The St. Louis Cardinals have placed Frank Mackie on the trade block. |
| 09-03-2057 | The St. Louis Cardinals have moved Frank Mackie, Tom Johnson, Ron Reid, and Rico Cabrinha to the active roster. The St. Louis Cardinals have moved Anthony Fischer, Alex Stephens, Edd Goodman, and Kenny Singleton to the inactive roster. |
| 01-01-2057 | The St. Louis Cardinals have moved James Panzer, Henri Creswell, Anthony Fischer, Andy Coley, Edd Goodman, Clay Murtha, Kenny Singleton, and Randy Williams to the active roster. The St. Louis Cardinals have moved Frank Mackie, Buzz Mendenhall, Ron Reid, Rico Cabrinha, Willie Campbell, Estes Stouffer, Aaron Smith, and Paul Stewart to the inactive roster. |
| 09-04-2056 | The St. Louis Cardinals have moved Rico Cabrinha, Paul Stewart, Frank Mackie, Ron Reid, and David Andrews to the active roster. The St. Louis Cardinals have moved Paul Johnson, Barrett Lorenti, Anthony Fischer, and Alex Stephens to the inactive roster. |
| 04-30-2056 | The St. Louis Cardinals have moved Barrett Lorenti to the active roster. The St. Louis Cardinals have moved Frank Mackie to the inactive roster. |
| 09-06-2055 | The St. Louis Cardinals have moved Frank Mackie, Ron Reid, and Rico Cabrinha to the active roster. The St. Louis Cardinals have moved Anthony Fischer, Alex Stephens, and Jodie Farquhardt to the inactive roster. |
| 01-17-2055 | The St. Louis Cardinals have moved Anthony Fischer, Alex Stephens, Lawrence Porter, Alden Bauer, Clinton Gordon, Thron Wolf, and Bill Staubach to the active roster. The St. Louis Cardinals have moved Jeff Rowland, Claude Williams, Frank Mackie, Ron Reid, Willie Campbell, David Andrews, and Paul Stewart to the inactive roster. |
| 09-13-2054 | The St. Louis Cardinals have moved Frank Mackie, Ron Reid, and Paul Johnson to the active roster. The St. Louis Cardinals have moved Anthony Fischer, M.L. Zupek, and Bill Staubach to the inactive roster. |
| 12-15-2053 | The St. Louis Cardinals have moved Henri Creswell, Larry Osborne, Anthony Tripoli, and Tiny Lund to the active roster. The St. Louis Cardinals have moved Frank Mackie, Paul Leber, Willie Campbell, and Paul Johnson to the inactive roster. |
| 09-01-2053 | The St. Louis Cardinals have moved Leon Brown, Frank Mackie, Ron Reid, and Tom Johnson to the active roster. The St. Louis Cardinals have moved Sean Howell, Mickey Dottley, and Larry Osborne to the inactive roster. |
| 01-06-2053 | The St. Louis Cardinals have moved Mickey Dottley, Larry Osborne, Andy Trafton, and Thron Wolf to the active roster. The St. Louis Cardinals have moved Frank Mackie, Ron Reid, Willie Campbell, and Paul Johnson to the inactive roster. |
| 09-02-2052 | The St. Louis Cardinals have moved Vic Schmaehl, Paul Johnson, Frank Mackie, and Ron Reid to the active roster. The St. Louis Cardinals have moved Pete Dunsmore, James Thomas, Paul Stewart, and Mike Levenick to the inactive roster. |
| 08-05-2052 | The St. Louis Cardinals have moved Zack Evans, Pat Goganious, Mike Levenick, and James Rankin to the active roster. The St. Louis Cardinals have moved Pinky Caranci, Dave Adams, Frank Mackie, and Derrick Kamp to the inactive roster. |
| 12-10-2051 | The St. Louis Cardinals have moved Frank Mackie and Major Response to the active roster. The St. Louis Cardinals have moved Jeff Rowland to the inactive roster. |
| 11-27-2051 | The St. Louis Cardinals have moved Mike Babich to the active roster. The St. Louis Cardinals have moved Frank Mackie to the inactive roster. |
| 11-26-2051 | Frank Mackie of the St. Louis Cardinals is injured with a shoulder muscle strain and is expected to be out for approximately 14 days. |
| 09-04-2051 | The St. Louis Cardinals have moved M.L. Zupek, Frank Mackie, and Ron Reid to the active roster. The St. Louis Cardinals have moved Adrian Branch, Pete Dunsmore, and Tom Johnson to the inactive roster. |
| 01-02-2051 | The St. Louis Cardinals have moved Jeff Rowland, Mike Banks, Victor Barnum, Pete Dunsmore, James Thomas, Paul Stewart, and Mike Teague to the active roster. The St. Louis Cardinals have moved Claude Williams, Frank Mackie, Ron Reid, Vic Schmaehl, Willie Campbell, Paul Johnson, and Bob Latta to the inactive roster. |
| 11-21-2050 | The St. Louis Cardinals have moved Frank Mackie to the active roster. The St. Louis Cardinals have moved Mike Banks to the inactive roster. |
| 11-14-2050 | The St. Louis Cardinals have moved Pete Dunsmore to the active roster. The St. Louis Cardinals have moved Frank Mackie to the inactive roster. |
| 11-13-2050 | Frank Mackie of the St. Louis Cardinals is injured with a mild concussion and is expected to be out for approximately 5 days. |
| 09-05-2050 | The St. Louis Cardinals have moved Frank Mackie, Ron Reid, and M.L. Zupek to the active roster. The St. Louis Cardinals have moved Karl Campofreda, Ed Latzke, and Dave Johnson to the inactive roster. |
| 01-09-2050 | The St. Louis Cardinals have moved Dave Johnson, Robert Barnett, Vernon Watson, Victor Barnum, and Charlie Watts to the active roster. The St. Louis Cardinals have moved Paul Johnson, Mike Bellisari, Vic Schmaehl, Frank Mackie, and Claude Williams to the inactive roster. |
| 12-06-2049 | The St. Louis Cardinals have moved Frank Mackie and Potsy Steele to the active roster. The St. Louis Cardinals have moved Mike Dalton and Derrick Gardner to the inactive roster. |
| 10-31-2049 | The St. Louis Cardinals have moved Allen Foster and Mike Banks to the active roster. The St. Louis Cardinals have moved Bill Mills and Frank Mackie to the inactive roster. |
| 10-31-2049 | Frank Mackie of the St. Louis Cardinals is injured with an ankle ligament sprain and is expected to be out for approximately 31 days. |
| 09-06-2049 | The St. Louis Cardinals have moved Paul Johnson, M.L. Zupek, Bob Latta, Vic Schmaehl, and Frank Mackie to the active roster. The St. Louis Cardinals have moved Curtis Watters, Ed Latzke, James Green, Victor Barnum, and Charlie Watts to the inactive roster. |
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