| Date | Transaction |
| 02-28-2111 | David Santiago has retired from football. |
| 09-05-2107 | The Winnipeg Jets have waived David Santiago. |
| 12-19-2106 | David Santiago of the Winnipeg Jets is injured with a knee derangement and is expected to be out for approximately 21 days. |
| 12-12-2106 | The Winnipeg Jets have moved David Santiago, Gus Bailey, Terry Nichols, and Frank Nairne to the active roster. The Winnipeg Jets have moved Mark Lemek, Chuck Essink, Ivory Taliaferro, and Sean Crawford to the inactive roster. |
| 10-10-2106 | The Winnipeg Jets have moved Damian Turley to the active roster. The Winnipeg Jets have moved David Santiago to the inactive roster. |
| 09-26-2106 | The Winnipeg Jets have moved David Santiago to the active roster. The Winnipeg Jets have moved Gerry Diem to the inactive roster. |
| 09-05-2106 | The Winnipeg Jets have moved Damian Turley, Steve Noble, Michael Pittman, Ivory Taliaferro, Dick Moses, Sean Crawford, and John Latzke to the active roster. The Winnipeg Jets have moved David Santiago and Gerry Diem to the inactive roster. |
| 11-22-2105 | The Winnipeg Jets have moved David Santiago and Andy Beitsett to the active roster. The Winnipeg Jets have moved Bob Browner and Rocky Gibson to the inactive roster. |
| 11-16-2105 | The Winnipeg Jets have acquired David Santiago from the waiver wire. |
| 11-09-2105 | The Montreal Oilers have waived David Santiago. |
| 10-19-2105 | The Montreal Oilers have moved Leon Office and Shawn Feggins to the active roster. The Montreal Oilers have moved David Santiago to the inactive roster. |
| 10-12-2104 | The Edmonton Snowmen have moved John Oberg and David Santiago to the active roster. The Edmonton Snowmen have moved John Jordan, Dan Schulz, and Dick McGrath to the inactive roster. |
| 09-22-2104 | The Edmonton Snowmen have moved Lloyd Manuel and Marsh Jaffurs to the active roster. The Edmonton Snowmen have moved David Santiago and Don Bradley to the inactive roster. |
| 09-22-2104 | The Edmonton Snowmen have moved Reggie Herchman and David Santiago to the active roster. The Edmonton Snowmen have moved Garland Johnson and Fu Manchu to the inactive roster. |
| 08-11-2104 | The Edmonton Snowmen have moved Donnie Williams, Chuck Blanks, Herbert McCullough, and Fu Manchu to the active roster. The Edmonton Snowmen have moved Deron Christensen, Dave Weston, Marsh Jaffurs, and David Santiago to the inactive roster. |
| 12-23-2103 | The Edmonton Snowmen have moved David Santiago and Rollin Sapp to the active roster. The Edmonton Snowmen have moved Cliff Grandberry to the inactive roster. |
| 12-02-2103 | The Edmonton Snowmen have moved Dick McGrath to the active roster. The Edmonton Snowmen have moved David Santiago to the inactive roster. |
| 11-20-2102 | The Las Vegas Ronins have moved David Santiago to the active roster. |
| 11-20-2102 | The Las Vegas Ronins have acquired David Santiago from the waiver wire. |
| 09-10-2102 | The Minnesota Jesuits have automatically waived David Santiago to comply with the 53-man roster limit. |
Linebacker